161 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilia ... Syndrome #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... /hypereosinophilia ... 1,500 cells/µL • Hypereosinophilia ... Differential #diagnosis #hematology ... #eosinophilia
Differential Diagnosis of Pulmonary Eosinophilia
Infection:
 • Helminthic: Loffler syndrome (Ascaris, hookworm, Strongyloides), Tropical pulmonary eosinophilia (lymphatic
Differential Diagnosis of Pulmonary ... Strongyloides), Tropical pulmonary ... Acute chronic pulmonary ... eosinophilia, Hypereosinophilic ... #Pulmonary #Differential
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Primary Eosinophilia ... : • Primary hypereosinophilic ... AI: EGPA, IgG-4 disease ... , Behcet disease ... Chronic inflammatory disease
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia ... Diagnosis and Management ... Alert_Oriented3 #Hypereosinophilia ... #diagnosis #hematology ... #differential #management
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... DRESS - AIN - Eosinophilic ... Leukemia - Primary Hypereosinophilic ... coyefish379 #Eosinophilia ... Diagnosis #Causes #hematology
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
Eosinophils (Eos ... ) and hypereosinophilia ... , IgG4-related disease ... TerrierBen #Eosinophils ... #hypereosinophilia
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases ... • Acute Eosinophilic ... , CV, renal • Hypereosinophilic ... #Lung #Diseases ... #pulmonary #differential
Hypereosinophilia (HE) Summary

 • Definition
 • When to Suspect?
 • A Partial Classification of Hypereosinophilia
 •
Hypereosinophilia ... Classification of Hypereosinophilia ... @ZhuoerXie #Hypereosinophilia ... #HE #hematology ... #diagnosis #management
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
Biologic therapy for eosinophilic ... • Peripheral eosinophils ... • Peripheral eosinophils ... #pharmacology #pulmonary ... #management