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Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Hypereosinophilia ... and Hypereosinophilic ... Syndrome #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
: • Primary hypereosinophilic ... B-cell lymphomas), Systemic ... AI: EGPA, IgG-4 disease ... , Behcet disease ... Chronic inflammatory disease
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... DRESS - AIN - Eosinophilic ... Lymphomas - Systemic ... Leukemia - Primary Hypereosinophilic ... Diagnosis #Causes #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... /hypereosinophilia ... 1,500 cells/µL • Hypereosinophilia ... Differential #diagnosis #hematology ... #eosinophilia
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases ... , hemoptysis; +systemic ... , CV, renal • Hypereosinophilic ... in 40%, mild; +systemic ... #Lung #Diseases
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
Eosinophils (Eos ... ) and hypereosinophilia ... , IgG4-related disease ... TerrierBen #Eosinophils ... #hypereosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia ... attributable to eosinophilia ... with blood eosinophilia ... Alert_Oriented3 #Hypereosinophilia ... #diagnosis #hematology
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Interstitial lung disease ... • Eosinophilic ... polyangiitis - Asthma. eosinophilia ... and C viruses. systemic
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... Systemic histoplasmosis ... Differential #Diagnosis #Hematology
Categories of disease to consider for eosinophilic meningitis: -Multicellular parasites (worms and flukes) -Fungal: Cocci -Atypical bacterial/mycobacterial: TB, syphilis,
Categories of disease ... to consider for eosinophilic ... Hypereosinophilic ... -Infiltrative disease ... #Eosinophilia #
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