2529 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... hypocalcemia Treatment ... of TLS: • Hypovolemia ... #TumorLysis #Syndrome
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... hyperkalemia) BRASH Treatment ... • Aggressive treatment ... intracellularly) • If hypovolemic ... DrEricStrong #BRASH #Syndrome
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Hypovolemia: Asthenia ... edema, compartment syndrome ... • No effective treatment ... Capillary #leak #syndrome
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... In persistent hypokalemia ... SRameshMD #Gitelman #Syndrome ... #Management #Treatment
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
Antiphospholipid syndrome ... Dissection, ASCVD, True hypovolemia ... ), Meds/Treatments
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Abdominal compartment syndrome ... compression • Hypovolemic ... Dehydration Shock Treatment ... criticalcare #algorithm #treatment
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... diuresis, Bartter's syndrome ... use), Gitelman's syndrome ... or induced) #Hypokalemia
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... Rhabdomyolysis Treatment ... pathophysiology #Hypokalemia
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
essential to determine treatment ... distributive, hypovolemic ... CCB, BB, BRASH syndrome ... cytokine release syndrome ... ↓ Preload): • HYPOVOLEMIC
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Emergencies Compartment Syndrome ... Syndrome usually ... including DM • Treatment ... Neurogenic Shock vs Hypovolemic ... diagnosis #management #treatment