348 results
Management of Immune Thrombocytopenia (ITP) . 

#Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune ... Thrombocytopenia ... #Idiopathic #Thrombocytopenic ... #Purpura #Immune ... #Thrombocytopenia
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
management of thrombocytopenia ... syndrome; ITP = immune ... thrombocytopenic ... purpura; TTP = ... purpura.)
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... consumption - Immune ... - ITP (immune ... - Non-immune ... purpura
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... → Palpable • Thrombocytopenia ... Vasculitis (LCV), Immune ... BrighamChiefs #Purpura
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Autoimmune thrombocytic purpura ... Heparin induced thrombocytopenia ... Target: Antigen-Ab immune
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... Hemolysis: • Immune-mediated
Differential for the Child with Petechiae or Purpura
 - Non-thrombocytopenic
 - Thrombocytopenia

#Diagnosis #Peds #Pediatrics #Petechiae #Purpura
with Petechiae or Purpura ... - Non-thrombocytopenic ... - Thrombocytopenia ... Pediatrics #Petechiae #Purpura ... #Differential #Thrombocytopenia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... ruling out an immune
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... presents in thrombocytopenic ... have idiopathic thrombocytopenic ... purpura. ... likely to have thrombocytopenia
Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
the Petechial / Purpuric ... DIC, Thrombotic Thrombocytopaenic ... Purpura Afebrile ... - Idiopathic Thrombocytopaenic ... Purpura By