101 results
Endocarditis - Duke Criteria - Major and Minor

MAJOR CRITERIA: 
 - Persistently +ve blood culture for
Endocarditis - Duke ... hemorhages - Immunologic ... criteria #Endocarditis ... #Duke #Criteria
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Petechiae Immunologic ... Septic Emboli Cause ... ischemic insult due ... Suspicion -> TEE • Duke ... Treat underlying cause
Major Brain Complications of Endocarditis
Abscess:
 • May be macro or micro and occur at site of
Complications of Endocarditis ... of the meninges due ... Ischemic stroke caused ... caseyalbin #endocarditis ... #neurological #neurology
Osler's Nodes in a patient with infective endocarditis

67yo presents with R occipital intraparenchymal hemorrhage (IPH) attributed
with infective endocarditis ... embolic phenomena due ... to endocarditis ... lesions (nontender, immunologic ... Node #infective #endocarditis
Duke's Criteria for Infective Endocarditis
Definite IE - Pathologic Criteria:
 • Pathologic lesions - vegetation or intracardiac
for Infective Endocarditis ... demonstrating active endocarditis ... Vascular phenomena • Immunologic ... febrilepodcast] #Duke ... criteria #Infective #Endocarditis
Stroke Etiologies
Hemorrhagic (IPH, SAH)
Ischemic
 - Large Vessel Atherosclerosis
 - Cardioembolic: Atrial fib, prosthetic valves, LV aneurysm,
, LV aneurysm, Endocarditis ... EricsMedicalLectures/ #Stroke #causes ... differential #diagnosis #neurology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... are caused by prerenal ... CONSIDER INTRINSIC CAUSES ... intrinsic etiologies due ... workup #diagnosis #nephrology
Central Retinal Vein Occlusion (CRVO)
 - Pathophysiology not fully understood; possibly due to thrombus located in
Occlusion (CRVO) - Pathophysiology ... understood; possibly due ... Second most common cause ... of vision loss due ... disease (Most common cause