26 results
Reduced DOAC Dosing for Atrial Fibrillation 

#DOAC #Reduced #Dosing #Reduction #Dose #Anticoagulation #Pharmacology #AFib #Renal #CKD
Reduced DOAC Dosing ... #Dosing #Reduction ... #Dose #Anticoagulation ... Pharmacology #AFib #Renal ... AtrialFibrillation #Indications
Stress Dose Steroids - Indications and Dosing

SUPPRESSED HPA AXIS:
 prednisone >20mg/day x 3 weeks or more
Stress Dose Steroids ... - Indications and ... StressDose #Steroids #Indications ... #Dosing #Endocrinology ... #Diagnosis #Management
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... - Differential Diagnosis ... Distributive Shock, HRS, Hypercalcemia ... Compartment Syndrome, Medications ... SCVMCMed #AKI #Acute
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
- Insulin (high ... dose) with glucose ... Antimicrobials Drug-induced ... hypomagnesemia #Medications ... #differential #diagnosis
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
- Differential Diagnosis ... (ALL) • Acute ... • High purine ... Sarcoidosis • Hypercalcemia ... #Algorithm #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Dosing Increase ... different than other medications ... very tolerable medication ... #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... 10 g QD (adjust dose ... g QD; increase dose ... patients sensitive to high ... #medications #pharmacology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... - Differential Diagnosis ... Congestion • Medications ... Infection-mediated, Drug-induced ... #Differential #Diagnosis
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
diarrhea / IBD Renal ... Loses - Medications ... abnormalities - Hypercalcemia ... - Hypokalemia ... #Differential #Diagnosis
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... Clenching of fist during ... phlebotomy High ... Medications 2. ... causes #potassium #high