14 results
diagnosis rheumatology treatment neurology disease guillain hemophagocytic hlh lymphohistiocytosis oncology symptoms anemia aplastic apml arteritis behcet calcium cerebritis cns common
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... response preceding infection ... #Syndrome #diagnosis ... #management #treatment
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... to a preceding infection ... the underlying pathophysiology ... #Syndrome #diagnosis ... #management #neurology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... ischemia, bowel infarction ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... CMV) • Epstein-Barr ... Anemia #oncology #hematology ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
+/- myocardial infarction ... inhibitors • Uveitis- Ophthalmology ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... can mimic common infections ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lupus Cerebritis Induction ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... vasculitis vs infection ... required +/- prompt ophthalmology ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
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