42 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Toxoplasmosis (CD4 ... Chorioretinitis • Diagnosis ... CNS Lymphoma (CD4 ... • Nocardia • Parasitic ... #causes #radiology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... auricular papules Clinical ... severity of the disease ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Artifact (redo CBC ... disorders • Celiac disease ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... salmonella, ...), Parasites ... Drugs, Unknown cause ... treatment #summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... decreased PLT count: CBC ... PT, aPTT(liver disease ... #Differential #Diagnosis ... #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Cr >2 mg/dL or CC ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... should be based on clinical ... Demyelinating disease ... caused by the JC ... opportunistic #InfectiousDiseases
Amebiasis - Balamuthia mandrillaris Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans
, disseminated disease ... mandrillaris #LifeCycle #diagnosis ... pathophysiology #infectiousdiseases ... #cdc #parasite
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... years - May have signs ... intervention CMC
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma Diagnosis ... Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... is also >100 CMC