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diagnosis differential management infectiousdiseases pulmonary rheumatology aids hiv neurology syndrome trypanosomiasis abscess american antibiotic brain chagas disease erythematosus failure fever
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Toxoplasmosis (CD4 ... lesions • 80% with lung ... Lymphoma (CD4 < ... • Nocardia • Parasitic ... differential #diagnosis #causes
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... present in 15% of cases ... Antimicrobial treatment ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Viral, Fungal, Parasite ... Tissue penetration (CNS ... (daptomycin in lungs ... • Secondary to Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... salmonella, ...), Parasites ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Diagnosis: • CBC ... Coccidioides • Parasite ... #differential #causes
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Lymphadenopathy, CNS ... factor • May cause ... possible in HIV PARASITIC ... differential #diagnosis #infectiousdiseases
Trypanosomiasis - Trypanosoma cruzi Life Cycle 1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
a blood meal (passes ... amastigotes in new infection ... pathophysiology #infectiousdiseases ... #cdc #parasite
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
six months of treatment ... ART ↑ improves CD4 ... pleural effusions, CNS ... PML), Confusion, visual ... unintentional weight loss, nausea
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... infections • ... Advanced HIV (CD4 ... Hematologic malignancy ... differential #diagnosis #infectiousdiseases
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... Interstitial nephritis • Distal ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment
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