13 results
Signaling Mechanism of PD-1 and PD-L1 and Inhibition of PD-1 Signaling in Microsatellite-Instability–High Cancers. MHC1 denotes
histocompatibility complex 1 #Pathophysiology ... #Honc #Pharm #PD1 ... MicrosatelliteInstability #NEJM
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
#Pathophysiology ... #GI #IM #NASH # ... NonAlcoholicFattyLiverDisease #NEJM
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
#Pathophysiology ... #Honc #IM #Spherocytosis ... HereditarySpherocytosis #NEJM
Hemorrhagic Shock Coagulopathy #Pathophysiology #Honc #Coagulopathy #HemorrhagicShock #NEJM
Coagulopathy #Pathophysiology ... #Honc #Coagulopathy ... HemorrhagicShock #NEJM
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
#Pathophysiology ... #Nephro #IM #LoopDiuretic ... NephronRemodeling #NEJM
A 48-year-old-man presented to the dermatology clinic with a whitish discoloration and hyperkeratosis of the first
Microscopic examination ... #Clinical #IM #InfectiousDisease ... RapidProgression #NEJM
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
#Pathophysiology ... #Nephro #IM #LoopDiuretic ... MechanismOfAction #Resistance #NEJM
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
#Pathophysiology ... #IM #Honc #Pharm ... Immunosuppression #NEJM
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
decreased reflexes Pathophysiology ... of AFB by smear microscopy ... intervention CMC IM
Squamous-Cell Carcinoma of the Tongue - Intraoral examination revealed a well-circumscribed superficial ulcer, with a homogeneous
Clinical #Pathology #Honc ... Tongue #Squamous #Microscopy ... #NEJM