25 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... • Deletion of critical ... delayed puberty -> Infertility ... , sleep apnea, cor ... Syndrome #genetics #pathophysiology
Upper endoscopy revealed a pigmented mass in the duodenal bulb (Panel A) and two additional masses
two additional masses ... duodenum (Panel B) #Clinical ... #GI #Derm #Honc ... Melanoma #Duodenum #EGD ... #Metastatic #NEJM
Gastric Cancer in Chest Radiograph - A plain radiograph of the chest showed a round, irregular
#Clinical #Radiology ... #GI #Honc #CXR ... #EGD #GastricCancer ... #NEJM
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
deficiencies that cause ... #Pathophysiology ... #Honc #IM #Spherocytosis ... HereditarySpherocytosis #NEJM
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... , dyspnea, +/- CXR ... + lab signs of end ... Lysis Syndrome: • Pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
help and inform clinical ... indicated, start CPR ... pericardiocentesis kit (eg ... strategy. ❼ If clinically ... a dramatic clinical
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
are in routine clinical ... been tested in clinical ... #Pathophysiology ... #IM #Honc #Pharm ... Immunosuppression #NEJM
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Blood cultures • CXR ... early disease) • CXR
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... fluid balance, and CXR