6 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
ANA - Non-specific ... common in SLE, autoimmune ... #diagnosis #table ... #rheumatology # ... antibodies
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Positive ANAAutoimmune ... but often not specific ... #rheumatology #diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... searched for when ANA ... erythematosus #diagnosis #rheumatology ... #table #ANA
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
age) Autoimmune ... hypofunction • Antibodies ... Anti-Ro/SSA ab (specific ... • Antinuclear antibodies ... Sjogrens #Syndrome #Rheumatology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
features that are specific ... Predisposing conditions: Autoimmune ... heart valves • MRI ... - Infectious Diseases ... Marantic #diagnosis #table
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
cartilage in the body (Autoimmune ... Sarcoidosis • Behcet disease ... not sensitive or specific ... Anti-Matrilin-1 Ab ○ Antibodies ... Polychondritis #rheumatology