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diagnosis ana antinuclear autoantibodies vasculitis abnormal aptt associations causes classification clinical coagulation erythematosus hematology lupus msas myositis patterns prolonged pt
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Antibodies (MSAs ... , TIF1y, NXP2, Mi ... clinical #diagnosis #rheumatology ... #table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... Associations ANA - Non-specific ... #diagnosis #table ... #rheumatology # ... antibodies
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... but often not specific ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... antiphospholipid antibodies ... antiphospholipid antibodies ... Causes #diagnosis #differential ... #hematology #coagulation
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Associated - ANCA specific ... Differential ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... oligoclonal bands • MRI ... Pauci Immune (ANCA specific ... #Diagnosis #Rheumatology
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