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hematology hemolytic cold differential oncology agglutinin antibodies autoantibodies causes chronic cll comparison disease erythematosus extravascular gammopathies hemeonc hemolysis intravascular leukemia
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - ... Table Warm AIHA ... (48-70%) Cold AHA ... Cold Agglutinin Disease ... #Diagnosis #Table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... common in SLE, autoimmune ... microsomal) - Autoimmune ... #diseases #diagnosis ... #table #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (AIHA) "Warm" ( ... (AIHA)"Cold" (usually ... , Copper and lead ... #hematology #anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... cytopenias (ITP, AIHA ... chemotherapy for low-risk disease ... lymphadenopathy and ... #hemeonc #diagnosis
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
clinical associations ... Autoimmune diseases ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... focal lesions on MRI ... autoimmune diseases ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Viral infection, autoimmune ... anemia • Cold ... CLL (older) • Autoimmune ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Non-autoimmune ... rheumatologic diseases ... Hematologic: • AIHA ... lymphopenia, low PLT • Anemia ... #Rheumatology
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