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hematology hemolytic differential agglutinin aiha antibodies autoantibodies causes comparison disease extravascular gammopathies hemolysis intravascular mgus monoclonal multiplemyeloma oncology urticaria
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... AHA (16-32%) • ... Agglutinin Disease ... #Table #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... common in SLE, autoimmune ... microsomal) - Autoimmune ... #diseases #diagnosis ... #table #rheumatology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
clinical associations ... Autoimmune diseases ... #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (AIHA)"Cold" (usually ... (e.g. primary cold ... , Copper and lead ... #hematology #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... • Symptoms of anemia ... anemia • Cold ... CLL (older) • Autoimmune ... #hematology #diagnosis
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... focal lesions on MRI ... autoimmune diseases ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
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