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diagnosis classification allergy ana antinuclear autoantibodies differential hypersensitivity reactions types arthritis associations comparison disease erythematosus laboratory pathophysiology patterns rheumatic rheumatoid
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... but often not specific ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... #diagnosis #rheumatology ... #table #ANA
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... others (RNP, aPL antibodies ... , Others: SRP, Mi ... • Scleroderma (Systemic ... #associations #table
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies ... When the specific ... during hemolytic disease ... lupus erythematosus ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Action: Allergen-specific ... Action: IgG/lgM antibodies ... reaction, Haemolytic disease ... glomerulonephritis, Systemic ... lupus erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Associated - ANCA specific ... inflammation Others: • Lupus ... lupus erythematosus ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... double-stranded DNA antibodies ... which are more specific
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