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symptoms autoantibodies comparison management neurology vasculitis arteritis arthritis associations autoimmune classification clinical erythematosus gca giantcell gout gouty inflammatory lupus mimickers
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Anti-MDA5, anti-Mi ... heliotrope, shawl sign ... #differential # ... #rheumatology # ... table
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
SLE-Related Auto-Antibodies ... : - ANA 95-100% ... Diagnosis and Lupus ... autoantibodies #signs ... #rheumatology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
NO prior signs ... NOT interpret MRI ... Differential diagnosis ... Has blooming on MRI ... #msk #rheumatology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... Lack of UMN/LMN signs ... EMG) studies • MRI ... #Diagnosis #neurology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... pain, such as MI ... Pericarditis #Symptoms #Signs ... Presentation #comparison #Table ... #Diagnosis
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 Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Bilateral signs ... out compressive myelopathies ... Antiamphiphysin antibodies ... management #neurology #differential
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... Diagnosis Framework ... purpura: strong sign ... ) pattern: antibodies ... #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Inflammatory Myopathies ... , drug-induced myopathies ... Gottron sign) ... • Shawl sign •
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