8 results
differential comparison inflammatory neurology antibodies associations autoantibodies autoimmune clinical dermatology idiopathic iims management msas myelitis rash specific transverse weakness
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Inclusion Body Myositis ... #Myopathies #myopathy ... #differential #diagnosis ... #comparison #rheumatology
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
, TIF1y, NXP2, Mi ... Mediated Necrotizing Myopathy ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
• Overlap Myositis ... Any inflammatory myopathy ... Inclusion body myositis ... #IIMs #diagnosis ... #rheumatology #
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... Anti-MDA5, anti-Mi ... Inclusion Body Myositis ... #comparison #rheumatology ... #table
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... proximal weakness Myopathy ... • Metabolic myopathies ... EMG) studies • MRI ... #Differential #Diagnosis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Peptide (CCP) • Myositis ... , Others: SRP, Mi ... #diagnosis #associations ... #table
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
the spinal cord (Myelopathy ... bouts of HTN Diagnostic ... Diagnosis: • ... out compressive myelopathies ... #diagnosis #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Inflammatory Myopathies ... , drug-induced myopathies ... RP-ILD), dermato-rheumatologic ... #Myopathy #rheumatology
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