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diagnosis hematology pulmonary ncpe noncardiogenic aa alveolar apml cardiology causes centralretinalartery crao differentiation gradient hypoxemia hypoxia management nonpalpable occlusion oncology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... Arterial Embolism ... #pathophysiology ... #hematology #differential ... #diagnosis #vascular
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework NCPE Pathophysiology: Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
- Differential ... Framework NCPE Pathophysiology ... • Pulmonary vascular ... • Pulmonary embolism ... #NCPE #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... • Septic emboli ... gangrenosum • Bacterial ... Vasculopathy #Purpura #Differential ... #nonpalpable #dermatology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
(NCPE) - Differential ... of the spiral arteries ... pupils Pulmonary Embolism ... multiple smaller emboli ... #causes #differential
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
Hypoventilation Syndrome, Muscular ... Mismatch: Pulmonary Edema ... Atelectasis, Pulmonary Embolism ... Gradient #alveolar #arterial ... Hypoxia #hypoxemia #differential
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Cardiogenic Embolism ... Valvular, arrhythmias ... upstream CRAO -> Arteriole ... Acute retinal edema ... Occlusion #CRAO #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Cathepsin G release → vascular ... myalgias, HoTN, edema ... initiation • Differential ... diagnosis #management #hematology
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