60 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... delayed puberty -> Infertility ... sleep apnea, cor pulmonale ... #genetics #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
ARDS to explain symptoms ... : 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Rheumatoid Nodules, Pulmonary ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Gestational Hypertension & Preeclampsia

Gestational Hypertension (gHTN) 
• BP > 140/90 
• Onset > 20 wks gestation
Elevated AST/ALT • Pulmonary ... Cerebral/visual symptoms ... Seizure HELLP Syndrome ... Classification #Diagnosis ... #Criteria #Obstetrics
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... • Rome IV Criteria ... Treatment: • Global ... Irritable #Bowel #Syndrome ... gastroenterology #treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... Criteria: • Elevated ... When present, symptoms ... #hematology
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) 
- Respiratory symptoms must have begun within one
Berlin Criteria ... Respiratory Distress Syndrome ... - Respiratory symptoms ... new or worsening symptoms ... #Diagnosis #CriticalCare
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... Pathophysiology ... onset widespread pulmonary ... Fat #Embolism #Syndrome ... #Symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... : >3 symptoms, or