18 results
diagnosis symptoms differential management hematology hypocalcemia pediatrics peds 21hydroxylasedeficiency 21ohd acromegaly algorithm bulimianervosa chondrocalcinosis clinical complications cppd cushings disease excess
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Parathyroid hormone–dependent ... hyperparathyroidism Genetic ... Hypercalcemia #Causes ... Differential #Diagnosis #Endocrinology
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 Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... delayed puberty -> Infertility ... #genetics #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... Signs / Symptoms ... Headaches • Nausea ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Causes of Hypocalcemia by Clinical Cause Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
low circulating calcium ... hypocalcemia - Genetic ... or parathyroid hormone ... Malabsorption syndrome ... Differential #Diagnosis #Endocrinology
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 Weight Gain / Obesity - Differential Diagnosis Algorithm Decreased Expenditure: • Sedentary Lifestyle • Smoking Cessation
• Cushing's Syndrome ... Hypothalamic Obesity Genetic ... Iatrogenic: • Drugs/Hormones ... Diagnosis #Algorithm #endocrinology ... #causes
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... • Other rare causes ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Myoedema in Hypothyroidism on Physical Exam Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... action of thyroid hormones ... reflex hammer, caused ... delayed uptake of calcium ... video #neurology #endocrinology
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 21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... of parathyroid hormone ... > Clearance of calcium ... CPPD #Disease #Signs ... #Symptoms #Pathophysiology
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