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diagnosis symptoms causes algorithm genetics gh growthhormone management pediatrics peds pituitary 21hydroxylasedeficiency 21ohd acromegaly alopecia bulimianervosa comatose comparison complications cushings
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table Diabetes Insipidus - Inadequate ADH SIADH -
Diabetes Insipidus vs Syndrome ... Comparison #Table #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Endocrinology
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
- Parathyroid hormone–related ... Other humoral syndromes ... disease - Williams syndrome ... Hypercalcemia #Causes #Differential ... #Diagnosis #Endocrinology
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 Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
common), growth hormone ... ) the anterior hormones ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... delayed puberty -> Infertility ... #genetics #pathophysiology
Hirsutism & Virilization - Differential Diagnosis Algorithm ADRENAL EXCESS Ovarian • Polycystic Ovarian Syndrome • Hyperthecosis • Tumor Adrenal
Virilization - Differential ... • Cushing's Syndrome ... Tumor Low Serum Hormone ... #Virilization #Differential ... Diagnosis #Algorithm #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology
Weight Gain / Obesity - Differential Diagnosis Algorithm Decreased Expenditure: • Sedentary Lifestyle • Smoking Cessation
Gain / Obesity - Differential ... Polycystic Ovarian Syndrome ... • Cushing's Syndrome ... Iatrogenic: • Drugs/Hormones ... Diagnosis #Algorithm #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup and Differential ... hypertension and signs ... renal bruit or signs ... of hormonal excess ... Vasculitis • Endocrinologic
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