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diagnosis pituitary differential genetics gh growthhormone pediatrics peds 21hydroxylasedeficiency 21ohd bulimianervosa causes comparison complications diabeticketoacidosis dka excess feedbackloop glftap hypercortisolism
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table Diabetes Insipidus - Inadequate ADH SIADH -
Diabetes Insipidus ... vs Syndrome of ... Comparison #Table #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Endocrinology
Cushing Syndrome - Signs and Symptoms Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome ... - Signs and Symptoms ... #Syndrome #Signs ... #Symptoms #diagnosis ... #endocrinology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... delayed puberty -> Infertility ... Obesity -> Type 2 diabetes ... #genetics #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
common), growth hormone ... Signs / Symptoms ... Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Clinical Effects of Large and Small Pituitary Tumours Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
pituitary apoplexy) Hormone ... ring size • Cushing's ... Pituitary #Tumors #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
(GH) Growth Hormone ... activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... melanocyte stimulating hormone ... #Syndrome #Hypercortisolism ... #Diagnosis #signs ... #symptoms #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
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