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differential hepatology liver hepatitis transaminitis chemistry child dili drug gastroenterology hepatocellular idiosyncratic induced interpretation limping management nwb pathway peds rvalue
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... #hepatology #algorithm ... Transaminitis #LFTs
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
suspicion of severe disease ... Non-accidental Injury ... #Limping #NWB #Algorithm ... #Child #Peds #Pediatrics ... #Diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... of cholestatic disease ... : > 2 • NASH, ... liver #chemistry #diagnosis ... transaminitis #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... : > 2 • NASH, ... #differential #diagnosis ... #algorithm #hepatology
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