107 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
Fungal biomarkers ... #Infections #Differential ... Ddx #Diagnosis #Fungal ... #Fungi #BDG #BDGlucan
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
M.kansasii, MAC) Fungal ... > 200: Endemic fungi ... Aspergillus spp, Endemic fungi ... cx (Bacterial, Fungal ... diagnosis #evaluation #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... component of many fungi ... cut-offs defined in clinical ... GM does not differentiate ... Sara Dong #Fungal
Causes of Hypercalcemia due to increased Vitamin D levels
 • The BIG 3:
levels • The BIG ... Tuberculosis • Fungal ... Silicone-induced granuloma, BCG-associated ... VitaminD #causes #differential
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Purple #Urine #Bag ... pathophysiology #clinical ... #photo #differential
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Evaluation and Differential ... the Anion Gap (AG ... pCO2. 4) The final ... Differential Diagnosis ... Evaluation #workup #Differential
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Antibiotic Failure - Differential ... , VTE • Wrong Bug ... bacteria: Viral, Fungal ... Immunocompromise Treatment ... • Secondary to Treatment
High-Res Chest CT Patterns - Differential Diagnosis Framework
Reticular:
 • Septal Thickening: Lymphangitic Carcinoma, Interstitial Edema, Alveolar
CT Patterns - Differential ... Infection (TB, Fungal ... PNA, Fibrosis, BAC ... Infection, Neoplasm (BAC ... #CT #Patterns #Differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
TTP VS HUS Big ... Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment
Septic Arthritis - Pathogens and Clinical Clues

Staphylococcus aureus 
Streptococcal spp. 
Neisseria gonorrhoeae 
Aerobic/Anaerobic 
Gram-negative bacteria 
Brucellosis
Pathogens and Clinical ... Fungal spp. ... Arthritis #Pathogens #Differential