41 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... common • Imaging: CXR ... Renal Failure Treatment ... • Supportive Care
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... - ACS, AKI, acute ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... /symptoms of active ... decreased reflexes Pathophysiology ... tissue damage - CXR
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... Tuberculosis Diagnosis ... and Culture • CXR ... disease • Check CXR
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... presents as an acute ... absent NK cell activity ... • Bicytopenia Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... Tuberculosis Diagnosis ... and Culture • CXR ... disease • Check CXR
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
indicated, start CPR ... • Diagnostic ... thoracotomy is a better treatment ... examination and vital signs ... Intraoperative #Checklist
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Pathogenesis and clinical ... tendon ruptures are ... warriors") • Acute ... TendonRupture #diagnosis ... #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... At least 3 of (Acute ... fluid balance, and CXR ... Reactions #hematology #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... Microglial cells are ... column Treatment ... by decreasing activity