34 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... common • Imaging: CXR ... organ dysfuxtion, ICU ... • Supportive Care
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
- Checklist VITALS ... ED triage notes are ... something has acutely ... get an EKG and CXR ... #diagnosis #workup
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... - ACS, AKI, acute ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
associated with acute ... Pathophysiology: ... : While it's a rare ... is not diagnostic ... peritonitis #IM #FM #ICU
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
indicated, start CPR ... • Diagnostic ... thoracotomy is a better treatment ... examination and vital signs ... Intraoperative #Checklist
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Pathogenesis and clinical ... tendon ruptures are ... warriors") • Acute ... TendonRupture #diagnosis ... #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... At least 3 of (Acute ... fluid balance, and CXR ... Reactions #hematology #diagnosis
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... Signs of poor perfusion ... Signs of congestion ... Cardiac cath if acute ... #criticalcare #icu
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... #management #treatment
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... headache, malaise) → Acute ... AP, ↑INR, ↑BUN/Cr ... care support, Transfer