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diagnosis liver blood causes hepatitis product syndrome aclf acute aflp algorithm anemia apml autoimmune basophilia basophils chemistry chronic differentiation extravascular
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... granules which are ... during an allergic reaction ... Irradiation • Cirrhosis ... Diagnosis #causes #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... Alcohol-Associated Hepatitis (AAH ... #Hepatology #gastroenterology ... #management #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
- Autoimmune (AIHA ... - Autoimmune (AIHA ... lactam antibiotics are ... Extravascular #Causes #differential ... #diagnosis #hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... If suspected, AIH ... Hepatitis (eg Viral) Management ... #Diagnosis #Management ... #Hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... • Acute Hemolytic ... Transfusion Related Acute ... Transfusion #diagnosis #management ... #hematology #reactions
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... infiltration) Differential ... Support - Critical care ... Liver #Pregnancy #hepatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Reaction ... Transfusion Related Acute ... Transfusions #diagnosis #management ... #hematology #reactions
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
: DAH, acute febrile ... initiation • Differential ... • Supportive Care ... APML #diagnosis #management ... #hematology #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Diagnosis and Management ... with or without cirrhosis ... Supportive care ... SpO2 > 88% • Management ... #treatment #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Mixed - Check Acute ... NT) - If both are ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
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