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diagnosis oncology treatment disease arthritis leukemia mds myelodysplastic adultonset algorithm aosd approach calcium cancer cardiology chestpain chronic cll cppd deposition
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... • Supportive Care ... Differentiation #Syndrome ... #management #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Conservative/supportive care ... Myelodysplastic #Syndrome ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... When Cancer Cells are ... #Leukemia #Hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Chronicity: • Acute ... Like in this case ... • Acute = Viral ... Joint #Pain #MSK #rheumatology ... #approach #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... anemia DDX: Rule Out ... Workup: • Complete ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
large numbers and are ... • Richter’s Syndrome ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Disease (AOSD) Rare ... Must rule out other ... NSAIDs, steroids (acutely ... Disease #AOSD #rheumatology ... #diagnosis #management
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
and Management ... that leads to an acute ... sex • Metabolic syndrome ... #diagnosis #management ... #treatment #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... diagnosis • Rule out ... #Rheumatology # ... diagnosis #management ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... insulting agent are ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
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