28 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... • Autoimmune diseases ... Adult-onset Still disease ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... severity Treatment - Acute ... #treatment #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
the time course (acute ... axial (spine, shoulders ... - Autoimmune Rheumatologic ... Differential #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... tumor • Non-bloody ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... granules which are ... translocation • Acute ... thrombocythemia • Acute ... Colitis and Crohn’s Disease
Diabetic foot infections (DFIs) is a common complication of longstanding diabetes, and it is associated with
Diabetic foot infections ... peripheral arterial disease ... cocci in many acutely ... Patients with a DFI should ... including vascular blood
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... presents as an acute ... should be diagnosed ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Benefits: ↓ Disease ... Thrombosis, ↓ Severe infection ... - Cuteanous: acute ... , should be known ... #sideeffects #rheumatology
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Diagnosis and Management ... : • 2 sets of blood ... cultures should ... afebrile • Acute ... gonorrhea #Diagnosis #Management
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... (AOSD) Rare inflammatory ... NSAIDs, steroids (acutely ... #AOSD #rheumatology ... #diagnosis #management