11 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... Conservative/supportive care ... Myelodysplastic #Syndrome ... #hematology #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... JAK2 mutation OR Abnormally ... present, symptoms, signs ... #Management #Summary ... #treatment #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... 500 mg QD until normal ... • Supportive Care ... Differentiation #Syndrome ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... insulting agent are ... #management #treatment ... #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... at the time of diagnosis ... ), liver (pain/abnormal ... #Management #Signs
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... within normal range ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Meningococcal), surgery, trauma ... the intensive care ... Guillain #Barre #Syndrome ... #diagnosis #management
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
The nail folds are ... seen in Reiter's syndrome ... Nail #Diseases #Abnormal ... #Pathology #Diagnosis ... #Clinical #Signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... diseases to exclude are ... purpura: Strong sign ... fluid (CSF) is abnormal ... #Rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
disease, which is a rare ... Histopathological Diagnoses ... phosphatase - Normal ... agonists #TAFRO #diagnosis ... #management #rheumatology