25 results
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... Trauma to the ... masked in the trauma ... Pathophysiology ... #Diagnosis #Signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... -> Trauma, disc ... #diagnosis #pathophysiology ... #signs #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine • Trauma ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Cushing's Syndrome ... gain (license photo ... What findings are ... Next diagnostic ... #Signs #MoonFacies
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare ... Carpal Tunnel Syndrome ... Overproduction #diagnosis ... #signs #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... • Mechanical Trauma ... ) - HELLP syndrome ... lactam antibiotics are ... #hematology #anemia
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
necrosis of hip (rare ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... • Supportive Care ... Differentiation #Syndrome ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... It is rare in presentation ... : HLH signs and ... insulting agent are ... management #treatment #hematology