46 results
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
each of the above photos ... Dacrocytes are found ... metaplasia, pernicious anemia ... some hemolytic anemias ... Path #BloodSmear #Blood
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... /blood loss (Fe ... rheumatologic, trauma ... Thrombocytosis #Differential
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... seen in hemolytic anemias ... is mechanical trauma ... Path #BloodSmear #Blood
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
the peripheral blood ... including chronic blood ... > 3: • Acute blood ... loss: Trauma, Gl ... #differential #
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate ... - Peripheral Blood ... #Hemolysis #Differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... deficiency of red blood ... Demand ischemia • Trauma ... disease #LDH #Lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... hyperlactatemia are ... removal from the blood ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... & Hypovolemia, Trauma ... Shock, Severe Anemia ... with negative lactate ... Lactic #Acidosis #Differential
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Two target cells are ... seen in the left photo ... present in the left photo ... with hemolytic anemias ... Path #BloodSmear #Blood
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
• Mechanical Trauma ... Microangiopathic hemolytic anemia ... - Drugs (Beta lactam ... antibiotics are ... Extravascular #Causes #differential