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clinical diagnosis blood path smear causes hematology cardiology dermatology endocarditis platelets skin thrombocytosis algorithm blurry canimorsus capnocytophaga codocytes cutaneous dacrocytes
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
each of the above photos ... Dacrocytes are found ... metaplasia, pernicious anemia ... some hemolytic anemias ... Clinical #Path #BloodSmear
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... rheumatologic, trauma ... Post-splenectomy or Asplenia ... Thrombocytosis #Differential
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Two target cells are ... seen in the left photo ... present in the left photo ... with hemolytic anemias ... Clinical #Path #BloodSmear
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
poikilocyte in the left photo ... cells in the right photo ... in congenital asplenia ... Clinical #Path #BloodSmear ... Howell #Jolly #Asplenia
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
In the right photo ... seen in hemolytic anemias ... microangiopathic hemolytic anemia ... is mechanical trauma ... Clinical #Path #BloodSmear
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency anemia ... infarction, Severe trauma ... period • Others: Asplenia ... Thrombocytosis #Platelets #Differential
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
In the left photo ... target cells are ... no significant anemia ... sickle unless they are ... Clinical #Path #BloodSmear
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ... and hemolytic anemias ... When spherocytes are ... very small, they are ... Clinical #Path #BloodSmear
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
• Mechanical Trauma ... Microangiopathic hemolytic anemia ... lactam antibiotics are ... Extravascular #Causes #differential ... diagnosis #hematology #anemia
Secondary Causes of Hypothermia - Differential Diagnosis Framework Definition: - Core temp < 35°C Infectious: - Sepsis Neuromuscular Disease: -
Hypothermia - Differential ... Definition: - Core ... Carcinomatosis - Uremia ... - Multi-system trauma ... #Hypothermia #Differential
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