15 results
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
each of the above photos ... Dacrocytes are found ... , thalassemia, and ... some hemolytic anemias ... #Clinical #Path
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
seen in the left photo ... and one in the ... present in the left photo ... with hemolytic anemias ... #Clinical #Path
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
In the right photo ... seen in hemolytic anemias ... is mechanical trauma ... uremic syndromes, and ... #Clinical #Path
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
In the left photo ... target cells are ... no significant anemia ... sickle unless they are ... #Clinical #Path
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ... hemolytic anemias ... When spherocytes are ... very small, they are ... #Clinical #Path
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
• Mechanical Trauma ... Microangiopathic hemolytic anemia ... lactam antibiotics are ... disease, Copper and ... Extravascular #Causes #differential
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
normal glucose, ask ... SGLT2 inhibitors and ... alkalosis}, APAP (rare ... linezolid U - Uremia ... Acidosis #diagnosis #differential
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
poikilocyte in the left photo ... and target cells ... in the right photo ... , thalassemia, and ... #Clinical #Path
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Noninflammatory • Bloody: Trauma ... neuropathy so trauma ... Like in this case ... #Joint #Pain #MSK ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... How many joints are ... Noninflammatory • Trauma ... #Joint #pain #Differential ... #Diagnosis #MSK