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hepatology differential causes management lfts acute chronic transaminitis aclf aih autoimmune chemistry cirrhosis criteria dili druginduced failure fatigue gastroenterology hepatocellular
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
Clinical diagnosis ... of Alcoholic Hepatitis ... (AH) • Onset ... #diagnosis #Alcoholic ... #Hepatitis #AH
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... survival in severe AH ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... HSV • Toxic: Alcohol ... #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... Drugs (MDMA), Alcohol ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... #Injury #Diagnosis ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... disease, liver ... Failure Infections Alcohol-Associated ... Injury (DILI) ... gastroenterology #management #diagnosis
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Algorithm Malignant ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Inflammatory • Alcoholic ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular ... ALT Ratios: • Alcoholic ... liver disease: ... #injury #hepatitis ... #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential Diagnosis ... Algorithm Severe ... • Cholestatic disease ... hepatitis • Drugs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... ALT Ratios: • Alcoholic ... liver disease: ... #chemistry #diagnosis ... #differential #Hepatology
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