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hepatology differential transaminitis injury abnormal arthritis biliary causes chemistry cholangitis chronic disease elevated gap globulin hbv hepatitis interpretation laboratory liverenzymes
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... 2-5x normal - Hemolysis ... #LFTs #transaminitis ... #differential #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... stone, Malignancy, PBC ... : < 1 • Cirrhosis ... #algorithm #hepatology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Algorithm • 12 ... : CBC with diff, ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #Algorithm #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Bile Ducts • PSC ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... • Others #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... : < 1 • Cirrhosis ... #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
/Liver failure ... or higher • Liver ... : • Viral hepatitis ... #diagnosis #workup ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... viremia or have cirrhosis ... • Monitor: CBC ... #HBV #Algorithm
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... IgM) levels • Hepatitis ... profile, including liver ... function tests (LFTs ... #diagnosis #testing
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... disease: Cirrhosis ... , PBC, PSC, Viral ... #differential #diagnosis
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