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differential hepatology transaminitis injury anemia biliary causes chemistry cholangitis elevated enzymes gap globulin hepatitis interpretation liverenzymes liverfunctiontests macrocytic microcytic pancytopenia
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Algorithm • 12 ... : CBC with diff, ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #Algorithm #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... function may be abnormal ... hepatitis: < 1 • Cirrhosis ... #algorithm #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... - Hemolysis, NASH ... #LFTs #transaminitis ... #differential #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... • Others #LFTs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... /Liver failure ... or higher • Liver ... #diagnosis #workup ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... hepatitis: < 1 • Cirrhosis ... #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... body mass index; FBC ... #LFTs #Abnormal ... #Algorithm #Hepatology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Normal range 11.5% ... acute blood loss, hemolysis ... #Diagnosis #Workup ... #Hematology #Microcytic
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... disease: Cirrhosis ... autoimmune hepatitis, PBC ... #differential #diagnosis
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