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diagnosis differential hepatology management secondary dermatology systemic acute bilirubin clinical dili generalized hyperbilirubinemia hyponatremia msk nephrology neurology pruritus radiology abdominal
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... presentation • Chronic ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... dechallenge • Acute or chronic ... e.g. ascites), Chronic ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... Injury (DILI) ... #ACLF #Acute #Chronic ... Cirrhosis #Hepatology #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Vascular Causes ... > 2 • NASH, Chronic ... : > 3 • Chronic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Renal Disease, Liver ... Reticulocytosis • Liver ... #Causes #Hematology
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... Differential Diagnosis Algorithm ... Traumatic brain injury ... Hypoxia, Uremia, Liver ... #Causes #neurology
Upper GI Bleed - Management Algorithm Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR Initial Stabilization Concern for
Bleed - Management Algorithm ... Stabilization Concern for Liver ... Consult GI ± EGD Causes ... GAVE (idiopathic, liver ... gastrointestinal #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... #Injury #Differential ... #Diagnosis #Causes ... #Acute #algorithm
Causes of Chronic Pelvic Pain (> 6 months in duration) - Differential Diagnosis Algorithm Co-morbidities: • Somatization
Causes of Chronic ... Differential Diagnosis Algorithm ... trigger points) • Injury ... Differential #Diagnosis #Algorithm ... #Causes #OBGyn
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Differential Diagnosis Algorithm ... Renal Failure • Liver ... Differential #Diagnosis #Algorithm ... #causes
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