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diagnosis differential causes management hepatology treatment hepatitis secondary dermatology ibd lfts pruritus systemic transaminitis abdominal acute aki celiac endocrinology generalized
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... presentation • Chronic ... disease 6-9 mo ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... disease, Hepatic ... e.g. ascites), Chronic ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... Injury (DILI) ... #ACLF #Acute #Chronic ... Cirrhosis #Hepatology #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • NASH, Chronic ... : > 3 • Chronic ... differential #diagnosis #algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Cirrhosis • Chronic ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... GTT, indirect bili ... current MELD - Chronic ... liver disease work ... Referral #Hepatology #Gastroenterology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... : > 3 • Chronic ... Unconjugated Bili
Perianal Crohn's Disease - IBD Algorithm • 5-40% w perianal fistula • ↑ risk if colonic
Perianal Crohn's Disease ... - IBD Algorithm ... medical therapy • Chronic ... Perianal #Crohns #Disease ... #gastroenterology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... • Anemia of Chronic ... Renal Disease, Liver ... Reticulocytosis • Liver ... Differential #Diagnosis #Algorithm
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm • Chronic Myocardial Injury: End
Diagnosis and Workup Algorithm ... • Chronic Myocardial ... Renal Disease, ... Structural Heart Disease ... (ie Sarcoid), Chronic
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