21 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
flexion of the knees ... While the pathophysiology ... for the hip/knee ... is that hip and knee ... despite severe disease
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Lyme Disease: Early ... several years after ... Large joints (knees ... WuidQ #Lyme #Disease ... #diagnosis #signs
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... most commonly the knees ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess after ... Cardiovascular disease ... Overproduction #diagnosis #signs ... endocrinology #pathophysiology
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
rubbing • Atopic diseases ... > Keratoconus Signs ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... Inflammatory eye disease ... infarction, coronary artery ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Inflammatory Joint Disease ... Degenerative Joint Disease ... commonly affects the knee ... JointPain #Diagnosis #pathophysiology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Unilateral • Signs ... deterioration after ... poor improvement after ... other auto-immune diseases ... #rheumatology #ophthalmology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... Signs of immunodeficiency ... appear 3-9 months after ... Agammaglobulinemia #XLinked #pathophysiology