9 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome, Headache ... #CNS #neurology ... #rheumatology #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... symptoms (headache ... Oral aphthae : SLE ... • Nonsurgical abdominal ... signs #symptoms #rheumatology
Headache Etiologies and Associated Spectrum of Severity of Disease by System
Critical, Emergent and Non-Emergent Causes
CNS, neurologic,
Headache Etiologies ... Disease by System Critical ... Non-Emergent Causes CNS ... vascular disease Ocular ... #differential #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... 50 years • New headache ... affects the skin, neurologic ... gut involvement, abdominal ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... Differential Diagnosis ... • Headache, mild ... #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus Clinical ... least 2 joints • Neurologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis ... #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... Blast Phase: • Headaches ... , weight loss, abdominal ... #Leukemia #Hematology ... #Oncology #Diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Sjogren's Syndrome Diagnosis ... gland) biopsy • Ocular ... salivary ducts Clinical ... Sjogrens #Syndrome #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
cough, chills, headache ... pulmonary symptoms • Rheumatologic ... has five major clinical ... Pulmonary 3) Abdominal ... osteoarticular, pulmonary, ocular