29 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... : B-symptoms, bruising ... hepatomegaly • Labs: anemia ... #hematology #WBC
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... #Dermatology #Rash ... Nikolsky #Algorithm #Differential ... #Ddxof
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... likelihood of negative clinical ... #differential # ... #WBC #CBC #hematology ... #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... IM Residency @CMC_IM ... #Management #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... pylori test (GI symptoms ... changes), high MCV anemia ... #Workup #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... proliferation rate ... Syndrome #TLS #diagnosis ... #management #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... anemia • Cold ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Vmphocytosis on routine CBC ... marrow failure with anemia ... #hemeonc #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Signs and Symptoms ... • Jaundice (later ... Diagnosis: • ... bile ducts Differential
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... decreased reflexes Pathophysiology ... intervention CMC ... IM Residency @CMC_IM