12 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Hyperosmolar Syndrome (HHS ... Polydipsia #dka #hhs ... #pathophysiology ... #comparison #endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... sarahthelyon #Diabetes ... #Medications #pharmacology ... #pathophysiology ... #endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... manage Type 2 diabetes ... of medications has ... #pharmacology #pharmacotherapy ... #endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... patients with diabetes ... signs/symptoms of HHS ... Pathophys #EM #IM ... #Endo #DKA #HHS
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Insulin, Inhibits Glucagon ... food and inhibit glucagon ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
Hypoglycemia Workup and Differential Diagnosis
Workup:
 • Sulfonylurea Labs
 • Anti-lnsulin Ab - Insulin Autoimmune Syndrome
 •
Measure glucose q6 hrs ... symptomatic or 72+hrs ... - 1mg IV Glucagon ... , 20 & 30 mins later ... Diagnosis #insulinoma #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... pancreas (GLP-1 = Glucagon-like ... Receptor #Agonists #Pharmacology ... #Summary #DM2 #diabetes ... #endocrinology
Intranasal Glucagon (Baqsimi)

The FDA has approved the first intranasal glucagon product! It's branded under the name
4 or older who has ... diabetes and has ... actually similar to IM ... reasons to use IM ... #Baqsimi #Pharmacology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
prevention of late ... minimum of 4-6 hrs ... treatment) 1:1000 IM ... Treatments #Management #pathophysiology