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diagnosis management differential spinalcord sclerosis signs syndromes acute aids als amyotrophic associated barre complications dementia disorder disorders encephalopathy gbs guillain
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Syndrome ->Cord ... #signs #symptoms ... #msk #orthopedics ... #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... Syndromes Spinal ... result in permanent neurologic ... Lower motor neuron symptoms ... #Cord #syndromes
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... hypercoagulable states ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... differential #algorithm
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
cord and nerve ... roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... the tuberculoma (later ... stage) • Headache
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
peaks between the ages ... monophasic Pathophysiology ... Hyperreflexia develops later ... Bilateral signs and/or symptoms ... diagnosis #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Altered mental status ... may precede the neurologic ... Etiology: • Pathophysiology ... Neurological symptoms ... diagnosis #management #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... (Spinal cord predominant ... objective evidence of neurologic ... diagnosis #management #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... Baltimore IM Residency ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... cord regions of ... features developing later ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
bone formation MSK ... canal & compress spinal ... cord itself -> ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms
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