44 results
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... steroids to treat infectious ... respiratory distress syndrome ... #Pharmacology # ... Management #Treatment
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
present in middle to late ... childhood and late ... to 8 years Clinical ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... proliferation rate ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... #summary #rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Statins - ETOH - Infection ... Dermatomyositis Clinical ... • Hypocalcemia/Late ... • HAGMA • Late
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Statins), ETOH Infection ... Dermatomyositis) AKI - Pathophysiology ... Iinitial rate: 1
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Clinical Triad ... year time period Late ... arterioles - Treatment ... David #Susac #Syndrome
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... CKD, CHF, high rate ... : No • Treatment ... Transfusion #Reactions #hematology
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... Manifestations and Treatment ... Albuminuria, nephrotic syndrome ... • Late latent ... early latent • Late
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Differential Diagnosis: Infection ... diagnosis #management #hematology