7 results
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
Syndrome • Leukonychia ... Syndrome • Onycholysis ... Plate Crumbling ... fingernail #pathology #differential ... #diagnosis #dermatology
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
Syndrome • Leukonychia ... Syndrome • Onycholysis ... Plate Crumbling ... fingernail #pathology #differential ... #diagnosis #dermatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Onycholysis - Plate ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... proliferation rate ... diagnosis #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Responsive to Treatment ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Resolution > 15 days Differentials ... disease: symptomatic treatment ... Hospital of Baltimore IM ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... diagnosis #management #hematology