34 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
medial half of 4th digits ... test • + Tinel sign ... Syndrome #Diagnosis #pathophysiology ... #signs #symptoms ... #msk
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... and vibration later ... Radiculopathy #MSK ... #diagnosis #signs ... #symptoms #pathophysiology
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
XR — scotty dog sign ... length due to tight ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology ... #signs #symptoms
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
proprioception, and light ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Marcus Gunn Pupil - Relative Afferent Pupillary Defect (RAPD)
Definition: Afferent loop of the pupillary light reflex
the pupillary light ... neuritis due to MS ... Later (1959), Levitan ... with the swinging light ... #Defect #RAPD #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... Type I cryo GN, Light-chain ... deposition disease (light ... Differential #Diagnosis #hematology
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
Hoffman's sign. ... middle finger. 2) Ask ... 3) Now strike lightly ... #Hoffmanns #Sign ... clinical #video #neurology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
tissue => Years later ... Severe, worse at night ... FrozenShoulder #pathophysiology ... diagnosis #symptoms #signs ... stages #staging #msk
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... proliferation rate ... diagnosis #management #hematology