13 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndrome ->Cord ... proprioception, and light ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperviscosity Syndrome ... of breath • Neurologic ... Epidural Spinal Cord ... • Paraplegia (late ... : Tumor Lysis Syndrome
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... proprioception, vibration, light
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Risk factor for Late ... mutations - Down syndrome ... memory • Aphasia, word-finding ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... capillary leak syndrome ... • Schnitzler syndrome ... Diagnosis #hematology #oncology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... MCTD, Sjogren syndrome ... Symptoms: • Back ... disorders #diagnosis #neurology ... differential #algorithm
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... the tuberculoma (later ... differential #TB #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic late-onset ... • Crystalline: light ... anemia due to cold ... Differential #Diagnosis #Oncology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Differential Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... seizures Life/sight-threatening ... #neurology #PHANTOMS
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... monophasic Pathophysiology ... Hyperreflexia develops later ... Bilateral signs and/or symptoms ... diagnosis #management #neurology