3 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... • Attempt if high ... Anaphylaxis, Acute Renal ... #management #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
• Present in high ... Pneumocystis pneumonia (late ... > 1.5) with a sensitivity ... 94 and 84% Renal ... Muscle: • Rhabdomyolysis
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Pathophysiology: ... Prognosis: • High ... #Hepatorenal #Syndrome ... #Hepatology #Nephrology